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Article

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

British journal of pharmacology - 1 Jan 2015

Knapman Alisa, Connor Mark

Abstract excerpt

UNLABELLED: There is significant variability in individual responses to opioid drugs, which is likely to have a significant genetic component. A number of non-synonymous single-nucleotide polymorphisms (SNPs) in the coding regions of the μ-opioid receptor gene (OPRM1) have been postulated to contribute to this variability. Although many studies have investigated the clinical influences of these μ-opioid receptor...

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Share to OPRM1 gene
Share to Polymorphism, Single Nucleotide
Share to Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Opioid, mu

Share to Signal Transduction

Source

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Identifiers

PMID: 24527749
DOI: 10.1111/bph.12644
PMCID: PMC4292952

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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