Article
The A118G single-nucleotide polymorphism of human μ-opioid receptor gene and use of labor analgesia.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Sept 2012
Pettersson Fatimah Dabo, Grönbladh Alfhild, Nyberg Fred, Sundström-Poromaa Inger, Åkerud Helena
Abstract excerpt
The human µ-opioid receptor (MOR) is the major site of action of endogenous opioids and most of the clinically used opioid analgesics. The single-nucleotide polymorphism (SNP), A118G of the MOR 1 gene (OPRM1), has been associated with altered pain perception. The aim of this study was to investigate whether this polymorphism of OPRM1 is associated with a number of pain-related behaviors during labor. In this...
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