Article
N-acetyltransferase 8, a positional candidate for blood pressure and renal regulation: resequencing, association and in silico study.
BMC medical genetics - 10 Apr 2008
Juhanson Peeter, Kepp Katrin, Org Elin, Veldre Gudrun, Kelgo Piret, Rosenberg Mai, Viigimaa Margus, Laan Maris
Abstract excerpt
BACKGROUND: Kidneys have an important function in blood pressure (BP) regulation and elevated BP may lead to kidney failure. Chr2p12-p13 region linked to BP traits in multiple studies harbours a potential candidate for BP and renal function, N-acetyltransferase 8 (NAT8) expressed in embryonic and adult kidney and associated with nephrotoxicity response. METHODS/RESULTS: We report the first study exploring NAT8 as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
