Article
HLA genomics in the third millennium.
Current opinion in immunology - 1 Oct 2005
Trowsdale John
Abstract excerpt
The MHC region contains several unique characteristics that set it apart as the most important region in the vertebrate genome in relation to disease. Recent data fit with the long-held view that the polymorphism of this region is driven by resistance to infection, although this is not yet proven. Interestingly, the MHC gene complex is associated with most, if not all, of the common autoimmune conditions. It has...
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