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HLA Genes: A Hallmark of Functional Genetic Variation and Complex Evolution.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Lenz Tobias L

Abstract excerpt

The major histocompatibility complex (MHC) with its highly polymorphic HLA genes represents one of the most intensely studied genomic regions in the genome. MHC proteins play a key role in antigen-specific immunity and are associated with a wide range of complex diseases. Despite decades of research and many advances in the field, the characterization and interpretation of its genetic and genomic variability...

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PMID: 38907887
DOI: 10.1007/978-1-0716-3874-3_1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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