Genetic variation and haplotype structures of innate immunity genes in eastern India.

doi:10.1016/j.meegid.2008.02.009

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Genetic variation and haplotype structures of innate immunity genes in eastern India.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 May 2008

Bairagya Bijan B, Bhattacharya Paramita, Bhattacharya Sujit K, Dey Biplab, Dey Uposoma, Ghosh Trina, Maiti Sujit, Majumder Partha P, Mishra Kankadeb, Mukherjee Sinchita, Mukherjee Souvik, Narayanasamy K, Poddar Sonia, Roy Neeta Sarkar, Sengupta Priya, Sharma Sangeeta, Sur Dipika, Sutradhar Debabrata, Wagener Diane K

Abstract excerpt

This study reports results of an extensive and comprehensive study of genetic diversity in 12 genes of the innate immune system in a population of eastern India. Genomic variation was assayed in 171 individuals by resequencing approximately 75kb of DNA comprising these genes in each individual. Almost half of the 548 DNA variants discovered was novel. DNA sequence comparisons with human and chimpanzee reference...

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PMID: 18396467
DOI: 10.1016/j.meegid.2008.02.009
PMCID: PMC2762703

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