Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Innate immunity and human diseases: from archaic introgression to natural selection].

Medecine sciences : M/S - 1 Dec 2016

Deschamps Matthieu, Quintana-Murci Lluís

Abstract excerpt

Throughout evolution, humans have had to face strong variation in environmental conditions, with pathogens being among the strongest threats that our species has encountered. The use of population genetic approaches provides novel insights into how natural selection imposed by pathogen pressures, in its different forms and intensities, has shaped the patterns of diversity of the human genome at the population...

Topics

Animals
Biological Evolution
Disease
Genetic Variation
Genetics, Population
Hominidae
Humans
Immunity, Innate
Neanderthals
Selection, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28044971
DOI: 10.1051/medsci/20163212011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Innate immunity and human diseases: from archaic introgression to natural selection].PMID 28044971Read ↗

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.Semantic proximity Read ↗

Adaptive variation in human toll-like receptors is contributed by introgression from both Neandertals and DenisovansSemantic proximity Read ↗

Introgression of Neandertal- and Denisovan-like Haplotypes Contributes to Adaptive Variation in Human Toll-like Receptors.Semantic proximity Read ↗

Evolutionary and population (epi)genetics of immunity to infection.Semantic proximity Read ↗

New insights into human immunity from ancient genomics.Semantic proximity Read ↗

From evolutionary genetics to human immunology: how selection shapes host defence genes.Semantic proximity Read ↗

Population genetic tools for dissecting innate immunity in humans.Semantic proximity Read ↗

Human immune diversity: from evolution to modernity.Semantic proximity Read ↗

Infectious Disease and the Diversification of the Human Genome.Semantic proximity Read ↗

Living in an adaptive world: Genomic dissection of the genus Homo and its immune response.Semantic proximity Read ↗

Dangerous liaisons: human genetic adaptation to infectious agents.Semantic proximity Read ↗

Ancient DNA reveals that natural selection has upregulated the immune system over the last 10,000 yearsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.