Article
Patterns of nucleotide sequence variation in ICAM1 and TNF genes in twelve ethnic groups of India: roles of demographic history and natural selection.
Journal of genetics - 1 Dec 2007
Sengupta Sanghamitra, Farheen Shabana, Mukherjee Neelanjana, Majumder Partha P
Abstract excerpt
We have studied DNA sequence variation in and around the genes ICAM1 and TNF, which play functional and correlated roles in inflammatory processes and immune cell responses, in 12 diverse ethnic groups of India, with a view to investigating the relative roles of demographic history and natural selection in shaping the observed patterns of variation. The total numbers of single nucleotide polymorphisms (SNPs)...
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