Article
Genetic diversity and purifying selection in West Nile virus populations are maintained during host switching.
Virology - 10 May 2008
Jerzak Greta V S, Brown Ivy, Shi Pei-Yong, Kramer Laura D, Ebel Gregory D
Abstract excerpt
To investigate differential evolutionary rates and selective forces of WNV in hosts and vectors, we measured the genetic diversity that arose during alternating passage in mosquitoes and birds. Within-host genetic diversity was monitored in each of three experimentally passed replicates, and the complete genome sequence of each WNV strain was determined after passage. The intrahost genetic diversity that arose...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
