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Article

Experimental Evolution of West Nile Virus at Higher Temperatures Facilitates Broad Adaptation and Increased Genetic Diversity.

Viruses - 22 Sept 2021

Fay Rachel L, Ngo Kiet A, Kuo Lili, Willsey Graham G, Kramer Laura D, Ciota Alexander T

Abstract excerpt

West Nile virus (WNV, Flaviviridae, Flavivirus) is a mosquito-borne flavivirus introduced to North America in 1999. Since 1999, the Earth's average temperature has increased by 0.6 °C. Mosquitoes are ectothermic organisms, reliant on environmental heat sources. Temperature impacts vector-virus interactions which directly influence arbovirus transmission. RNA viral replication is highly error-prone and increasing...

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Identifiers

PMID: 34696323
DOI: 10.3390/v13101889
PMCID: PMC8540194

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