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Article

The West Nile virus mutant spectrum is host-dependant and a determinant of mortality in mice.

Virology - 10 Apr 2007

Jerzak Greta V S, Bernard Kristen, Kramer Laura D, Shi Pei-Yong, Ebel Gregory D

Abstract excerpt

To define the impact of mosquitoes and birds on intrahost WNV population dynamics, the mutant spectra that arose as a result of 20 serial in vivo passages in Culex pipiens and young chickens were examined. Genetically homogeneous WNV was serially passaged 20 times in each host. Genetic diversity was greater in mosquito-passaged WNV compared to chicken-passaged WNV. Changes in the viral consensus sequence occurred...

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Identifiers

PMID: 17134731
DOI: 10.1016/j.virol.2006.10.029
PMCID: PMC1934562

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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