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Article

Frequent recombination events generate diversity within the multi-copy variant antigen gene families of Plasmodium falciparum.

International journal for parasitology - 1 Aug 2008

Frank Matthias, Kirkman Laura, Costantini Daniel, Sanyal Sohini, Lavazec Catherine, Templeton Thomas J, Deitsch Kirk W

Abstract excerpt

The human malaria parasite Plasmodium falciparum utilises a mechanism of antigenic variation to avoid the antibody response of its human host and thereby generates a long-term, persistent infection. This process predominantly results from systematic changes in expression of the primary erythrocyte surface antigen, a parasite-produced protein called PfEMP1 that is encoded by a repertoire of over 60 var genes in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18395207
DOI: 10.1016/j.ijpara.2008.01.010
PMCID: PMC2441941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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