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Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum

13 May 2019

Abstract excerpt

Malaria parasites possess the remarkable ability to maintain chronic infections that fail to elicit a protective immune response, characteristics that have stymied vaccine development and cause people living in endemic regions to remain at risk of malaria despite previous exposure to the disease. These traits stem from the tremendous antigenic diversity displayed by parasites circulating in the field. For...

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PMID: 31083650
DOI: 10.1371/journal.pbio.3000271

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