Article
Analysis of Plasmodium falciparum PfEMP-1/var genes suggests that recombination rearranges constrained sequences.
Molecular and biochemical parasitology - 30 Jul 1999
Ward C P, Clottey G T, Dorris M, Ji D D, Arnot D E
Abstract excerpt
The var genes of Plasmodium falciparum encode a family of parasite erythrocyte surface antigens, the PfEMP-1 proteins, which function as adhesion ligands for host endothelial and erythrocyte receptors. PfEMP-1 is extremely polymorphic although the extent of this variation in naturally transmitted...
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