Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia.

Schizophrenia research - 1 Apr 2008

Fatemi S Hossein, King David P, Reutiman Teri J, Folsom Timothy D, Laurence Jessica A, Lee Susanne, Fan Yu-Ti, Paciga Sara A, Conti Marco, Menniti Frank S

Abstract excerpt

Schizophrenia has a complex genetic underpinning and variations in a number of candidate genes have been identified that confer risk of developing the disorder. We report in the present studies that several single nucleotide polymorphisms (SNPs) and a two-SNP haplotype in PDE4B are associated with an increased incidence of schizophrenia in two large populations of Caucasian and African American patients. The SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Black People

Share to Chi-Square Distribution

Share to Cyclic Nucleotide Phosphodiesterases, Type 4

Share to Schizophrenia

Share to White People

Source

Identifiers

PMID: 18394866
DOI: 10.1016/j.schres.2008.01.029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia.PMID 18394866Read ↗

Association of PDE4B Polymorphisms with Susceptibility to Schizophrenia: A Meta-Analysis of Case-Control Studies.Semantic proximity Read ↗

The PDE4B gene confers sex-specific protection against schizophrenia.Semantic proximity Read ↗

Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorderSemantic proximity Read ↗

Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples.Semantic proximity Read ↗

Association of PDE4B polymorphisms and schizophrenia in Northwestern Han Chinese.Semantic proximity Read ↗

Phosphodiesterase 4B: Master Regulator of Brain SignalingSemantic proximity Read ↗

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.Semantic proximity Read ↗

Phosphodiesterase 4B genetic variants are not associated with antipsychotic-induced tardive dyskinesia.Semantic proximity Read ↗

Positive association of the PDE4B (phosphodiesterase 4B) gene with schizophrenia in the Japanese population.Semantic proximity Read ↗

Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population.Semantic proximity Read ↗

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.Semantic proximity Read ↗

Novel PDE10A transcript diversity in the human striatum: Insights into gene complexity, conservation and regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.