Article
Positive association of the PDE4B (phosphodiesterase 4B) gene with schizophrenia in the Japanese population.
Journal of psychiatric research - 1 Nov 2008
Numata Shusuke, Ueno Shu-Ichi, Iga Jun-Ichi, Song Hongwei, Nakataki Masahito, Tayoshi Shin'ya, Sumitani Satsuki, Tomotake Masahito, Itakura Mitsuo, Sano Akira, Ohmori Tetsuro
Abstract excerpt
The phosphodiesterase 4B (PDE4B) gene is located at 1p31, a susceptibility region for schizophrenia (SZ). Moreover, PDE4B interacts with DISC1, which is a known genetic risk factor for SZ. Recently, it was reported that the PDE4B gene is associated with SZ in Caucasian and African American popula...
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