Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Positive association of the PDE4B (phosphodiesterase 4B) gene with schizophrenia in the Japanese population.

Journal of psychiatric research - 1 Nov 2008

Numata Shusuke, Ueno Shu-Ichi, Iga Jun-Ichi, Song Hongwei, Nakataki Masahito, Tayoshi Shin'ya, Sumitani Satsuki, Tomotake Masahito, Itakura Mitsuo, Sano Akira, Ohmori Tetsuro

Abstract excerpt

The phosphodiesterase 4B (PDE4B) gene is located at 1p31, a susceptibility region for schizophrenia (SZ). Moreover, PDE4B interacts with DISC1, which is a known genetic risk factor for SZ. Recently, it was reported that the PDE4B gene is associated with SZ in Caucasian and African American populations. In this study, case-controlled association analyses were performed in the Japanese population to determine if...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Cyclic Nucleotide Phosphodiesterases, Type 4

Share to Genetic Linkage

Share to Genetic Markers

Share to Linkage Disequilibrium

Share to Schizophrenia

Source

Identifiers

PMID: 18329668
DOI: 10.1016/j.jpsychires.2008.01.013

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Positive association of the PDE4B (phosphodiesterase 4B) gene with schizophrenia in the Japanese population.PMID 18329668Read ↗

Association of PDE4B Polymorphisms with Susceptibility to Schizophrenia: A Meta-Analysis of Case-Control Studies.Semantic proximity Read ↗

Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples.Semantic proximity Read ↗

Association of PDE4B polymorphisms and schizophrenia in Northwestern Han Chinese.Semantic proximity Read ↗

Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population.Semantic proximity Read ↗

Association analysis of PDE4B polymorphisms with schizophrenia and smooth pursuit eye movement abnormality in a Korean population.Semantic proximity Read ↗

The PDE4B gene confers sex-specific protection against schizophrenia.Semantic proximity Read ↗

PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia.Semantic proximity Read ↗

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.Semantic proximity Read ↗

Case-control association study of Disrupted-in-Schizophrenia-1 (DISC1) gene and schizophrenia in the Chinese population.Semantic proximity Read ↗

Gene polymorphisms of DISC1 is associated with schizophrenia: Evidence from a meta-analysis.Semantic proximity Read ↗

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.Semantic proximity Read ↗

Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorderSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.