Article
Phosphodiesterase 4B genetic variants are not associated with antipsychotic-induced tardive dyskinesia.
International clinical psychopharmacology - 1 Sept 2010
Souza Renan P, Remington Gary, Meltzer Herbert Y, Lieberman Jeffrey A, Kennedy James L, Wong Albert H C
Abstract excerpt
Phosphodiesterase 4B (PDE4B) has been evaluated as a genetic risk factor for schizophrenia. Selective PDE4 inhibitor drugs have antipsychotic-like effects and reduce tardive dyskinesia-like movements in animal models. We investigated whether PDE4B genetic variants are associated with antipsychoti...
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