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Article

Association of PDE4B polymorphisms and schizophrenia in Northwestern Han Chinese.

Human genetics - 1 Jul 2012

Guan Fanglin, Zhang Chen, Wei Shuguang, Zhang Hongbo, Gong Xiaomin, Feng Jiali, Gao Chengge, Su Rong, Yang Huanming, Li Shengbin

Abstract excerpt

The phosphodiesterase 4B (PDE4B) is a candidate susceptibility gene for schizophrenia (SCZ), interacting with DISC1, a known genetic risk factor for SCZ. To examine if variants within PDE4B gene are associated with SCZ in Northwestern Han Chinese, and if these effects vary in gender-specific subgroup, we analyzed 20 SNPs, selected from previous studies and preliminary HapMap data analyses with minor allele...

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Identifiers

PMID: 22160351
DOI: 10.1007/s00439-011-1120-8

Genes

DISC1
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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