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Article

Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.

British journal of cancer - 6 May 2008

Kim M S, Jeong E G, Yoo N J, Lee S H

Abstract excerpt

Mounting evidence indicates that alterations of AKT signalling play important roles in cancer development. An earlier study discovered an oncogenic AKT1 gene mutation (AKT1 E17K) in breast, colorectal and ovarian cancers. The aim of this study was to see whether the AKT1 E17K mutation is common in breast, colorectal, lung, gastric and hepatocellular carcinomas and acute leukaemias. We analysed the presence of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18392055
DOI: 10.1038/sj.bjc.6604212
PMCID: PMC2391109

Genes

AKT1
AKT2
AKT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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