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Article

Mutational Analysis of <i>AKT1, AKT2</i> and <i>AKT3</i> Genes in Common Human Carcinomas

1 Jan 2006

Abstract excerpt

<i>Objective:</i> Mounting evidence indicates that alterations in AKT proteins play an important role in the pathogenesis of cancer. The objective of this study was to see whether common human carcinomas harbor <i>AKT</i> mutations that might contribute to the development of cancer. <i>Methods:</i> We performed mutational analysis of the kinase domains of...

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PMID: 17047397
DOI: 10.1159/000096289

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