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Article

Inheritance of immune polarization patterns is linked to resistance versus susceptibility to Cryptococcus neoformans in a mouse model.

Infection and immunity - 1 Jun 2008

Chen Gwo-hsiao, McNamara David A, Hernandez Yadira, Huffnagle Gary B, Toews Galen B, Olszewski Michal A

Abstract excerpt

Genetic background variation between inbred strains accounts for different levels of susceptibility to Cryptococcus neoformans in the mouse infection model. To elucidate the inheritance of immunophenotypic traits and their associations with clearance outcomes during cryptococcal infection, we compared C57BL/6, BALB/c, and their first-generation hybrid, CB6F1 (F1), mice. Mice from each group were infected with C....

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Identifiers

PMID: 18391002
DOI: 10.1128/IAI.01143-07
PMCID: PMC2423067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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