Article
Association study between catechol-O-methyltransferase polymorphisms and uterine leiomyomas in a Japanese population.
Clinical and experimental obstetrics & gynecology - 1 Jan 2008
Morikawa J, Yoshida S, Kennedy S, Takemura N, Sugimoto M, Kitao K, Deguchi M, Ohara N, Maruo T
Abstract excerpt
PURPOSE: To investigate a possible association between uterine leiomyomas and catechol-O-methyltransferase (COMT) polymorphisms in a Japanese population. METHODS: We compared the allele frequencies and genotype distributions of the exon 4 NlaIII restriction site polymorphism (RSP), the P2 promoter HindIII RSP at -1217, and the exon 6 BglI RSP in the COMT gene in 250 leiomyoma cases and 182 controls using...
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