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Article

Polymorphism of catechol-o-methyltransferase and uterine leiomyoma.

Molecular and cellular biochemistry - 1 Mar 2013

Ates Omer, Demirturk Fazli, Toprak Muhammet, Sezer Saime

Abstract excerpt

Uterine leiomyoma (ULM) is the most common gynecological benign tumor that is affecting around 20-50 % of women over the age of 30. Although its molecular pathogenesis is still unknown, ULM has a multifactorial etiology determined by both genetics and environmental factors. The present study was designed to find out whether Val158Met polymorphism in the catechol-o-methyltransferase (COMT) gene is associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23238870
DOI: 10.1007/s11010-012-1540-3

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphism of catechol-o-methyltransferase and uterine leiomyoma.PMID 23238870Read ↗

The associations between the Val158Met in the catechol-O-methyltransferase (COMT) gene and the risk of uterine leiomyoma (ULM).Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism is associated with increased risk of multiple uterine leiomyomas either positive or negative for MED12 exon 2 mutations.Semantic proximity Read ↗

Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups.Semantic proximity Read ↗

Val153Met polymorphism of catechol-O-methyltransferase and prevalence of uterine leiomyomata.Semantic proximity Read ↗

Association study between catechol-O-methyltransferase polymorphisms and uterine leiomyomas in a Japanese population.Semantic proximity Read ↗

The catechol-O-methyltransferase (COMT) gene polymorphism and prevalence of uterine fibroids.Semantic proximity Read ↗

Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

[Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer].Semantic proximity Read ↗

The Effect of Estrogen-Related Genetic Variants on the Development of Uterine Leiomyoma: Meta-analysis.Semantic proximity Read ↗

Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: a case-control study.Semantic proximity Read ↗

Lack of associations of the COMT Val158Met polymorphism with risk of endometrial and ovarian cancer: a pooled analysis of case-control studies.Semantic proximity Read ↗

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