Article
BRAF and K-RAS mutation in a Greek papillary and medullary thyroid carcinoma cohort.
Anticancer research - 1 Jan 2000
Goutas Nikolaos, Vlachodimitropoulos Dimitrios, Bouka Myrto, Lazaris Andreas C, Nasioulas George, Gazouli Maria
Abstract excerpt
BACKGROUND: The genes RAS and BRAF have been shown to be frequently mutated in human thyroid carcinomas. The aim of this study was to genotype a cohort of 55 sporadic papillary thyroid carcinomas (PTC) and 44 sporadic medullary thyroid carcinomas (MTC) for the K-RAS codon 12 and BRAF codon 600 mutations. MATERIALS AND METHODS: K-RAS and BRAF mutations were characterized by an enhanced polymerase chain reaction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
