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Article

Polymorphisms of death pathway genes FAS and FASL and risk of premalignant gastric lesions.

Anticancer research - 1 Jan 2000

Hsu Ping-I, Lu Pei-Jung, Wang E-Ming, Ger Luo-Ping, Lo Gin-Ho, Tsay Feng-Woei, Chen Tai-An, Yang Hsiao-Bai, Chen Hui-Chun, Lin Weir-Sen, Lai Kwok-Hung

Abstract excerpt

BACKGROUND: Tumorigenesis is a multistep process that begins with the abrogation of normal controls of apoptosis and cell proliferation, and the FAS receptor-ligand system is a key regulator of apoptosis. The aim of this study was to investigate whether functional polymorphisms of death pathway genes (FAS and FASL) are associated with the development of gastric atrophy and intestinal metaplasia. PATIENTS AND...

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Source

Identifiers

PMID: 18383830

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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