Article
Functional polymorphisms in FAS/FASL system contribute to the risk of occurrence but not progression of gastric cardiac adenocarcinoma.
Hepato-gastroenterology - 1 Jan 2000
Zhang Weimin, Li Chen, Wang Jing, He Chao
Abstract excerpt
BACKGROUND/AIMS: Loss of FAS and gain of aberrant FASL expression are common features of malignant transformation. This study was designed to investigate whether the functional polymorphisms of FAS-1377 G/A (rs2234767) and FASL-844 T/C (rs763110) have an effect on the occurrence and progression of gastric cardiac adenocarcinoma (GCA). METHODOLOGY: Associations of the FAS and FASL polymorphisms with GCA were...
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