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Fas -670A/G (rs1800682) polymorphism and digestive cancer risk in Asians: a meta-analysis.

Genetic testing and molecular biomarkers - 1 Jul 2014

Yuan Hai-Peng, Liu Qing-Dong, Li Gai-Qin, Cong Yan-Qun

Abstract excerpt

OBJECTIVES: Tumorigenesis is a multistep process that begins with the abrogation of normal controls of apoptosis and cell proliferation, and the Fas receptor-ligand system is a key regulator of apoptosis. The Fas -670 A/G single-nucleotide polymorphism (SNP) has been demonstrated to affect the expression of the Fas gene by altering the transcriptional activity in this gene's promoter. However, the association...

Topics

Biomarkers, Tumor
China
Gastrointestinal Neoplasms
Humans
Molecular Epidemiology
Mutation
Polymorphism, Single Nucleotide
fas Receptor

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24800976
DOI: 10.1089/gtmb.2014.0032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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