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Article

FAS and FAS ligand polymorphisms in the promoter regions and risk of gastric cancer in Southern China.

Biochemical genetics - 1 Aug 2009

Wang Meilin, Wu Dongmei, Tan Ming, Gong Weida, Xue Hengchuan, Shen Hongbin, Zhang Zhengdong

Abstract excerpt

The FAS and FAS ligand (FASLG) system plays a key role in regulating apoptotic cell death, and corruption of this signaling pathway has been shown to participate in tumorigenesis. Functional promoter polymorphisms of the FAS and FASLG genes can alter transcriptional activities and thus alter risk of cancer. We hypothesized that the FAS -1377G>A, FAS -670A>G, and FASLG -844T>C polymorphisms in the promoter regions...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19565204
DOI: 10.1007/s10528-009-9264-0

Genes

FAS
FASLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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