Article
Interleukin-23 receptor single nucleotide polymorphisms in ulcerative colitis. A study in Iranian populations.
Clinics and research in hepatology and gastroenterology - 1 Jun 2014
Ebrahimi Daryani Nasser, Najmi Varzaneh Farnaz, Hedayat Mona, Taher Mohammad, Farhadi Elham, Mahmoudi Mahdi, Nicknam Mohammad Hossein, Bashashati Mohammad, Rezaei Nima
Abstract excerpt
BACKGROUND/OBJECTIVE: Genetic factors seem to play an important role in the pathogenesis of ulcerative colitis (UC). Genome wide association studies showed a highly significant association between interleukin 23 receptor (IL23R) single nucleotide polymorphisms (SNPs) and Crohn's disease; however, there are contrary results regarding the disease-modifying effects of IL23R variants in UC. This study was performed...
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