Article
Effect of destrin mutations on the gene expression profile in vivo.
Physiological genomics - 12 Jun 2008
Verdoni Angela M, Aoyama Natsuyo, Ikeda Akihiro, Ikeda Sakae
Abstract excerpt
Remodeling of the actin cytoskeleton through actin dynamics (assembly and disassembly of filamentous actin) is known to be essential for numerous basic biological processes. In addition, recent studies have provided evidence that actin dynamics participate in the control of gene expression. A spontaneous mouse mutant, corneal disease 1 (corn1), is deficient for a regulator of actin dynamics, destrin (DSTN, also...
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