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Article

Microarray analysis of iris gene expression in mice with mutations influencing pigmentation.

Investigative ophthalmology & visual science - 1 Jan 2011

Trantow Colleen M, Cuffy Tryphena L, Fingert John H, Kuehn Markus H, Anderson Michael G

Abstract excerpt

PURPOSE: Several ocular diseases involve the iris, notably including oculocutaneous albinism, pigment dispersion syndrome, and exfoliation syndrome. To screen for candidate genes that may contribute to the pathogenesis of these diseases, genome-wide iris gene expression patterns were comparatively analyzed from mouse models of these conditions. METHODS: Iris samples from albino mice with a Tyr mutation, pigment...

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Identifiers

PMID: 20739468
DOI: 10.1167/iovs.10-5479
PMCID: PMC3053276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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