Article
Abnormal epithelial homeostasis in the cornea of mice with a destrin deletion.
Molecular vision - 1 Jan 2008
Zhang W, Zhao J, Chen L, Urbanowicz M M, Nagasaki T
Abstract excerpt
PURPOSE: Dstn(corn1) mice lack normal destrin expression and develop corneal abnormality shortly after birth such as epithelial hyperplasia and total vascularization. Thus, the mice serve as a model for ocular surface disorders. To determine the nature of epithelial defects, we examined whether epithelial homeostasis is altered in these corneas. METHODS: Dstn(corn1) mice were crossed with ubiquitous GFP mice to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
