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Article

DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention.

Cancer letters - 18 Jul 2008

Paz-Elizur Tamar, Sevilya Ziv, Leitner-Dagan Yael, Elinger Dalia, Roisman Laila C, Livneh Zvi

Abstract excerpt

Efficient DNA repair mechanisms comprise a critical component in the protection against human cancer, as indicated by the high predisposition to cancer of individuals with germ-line mutations in DNA repair genes. This includes biallelic germ-line mutations in the MUTYH gene, encoding a DNA glycosylase that is involved in the repair of oxidative DNA damage, which strongly predispose humans to a rare hereditary...

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Identifiers

PMID: 18374480
DOI: 10.1016/j.canlet.2008.02.032
PMCID: PMC2563153

Genes

MUTYH
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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