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Article

Cytoplasmic dynein could be key to understanding neurodegeneration.

Genome biology - 1 Jan 2008

Banks Gareth T, Fisher Elizabeth M C

Abstract excerpt

A new mouse mutation, Sprawling, highlights an essential role for the dynein heavy chain in sensory neuron function, but it lacks the ability of other known heavy-chain mutations to ameliorate neurodegeneration due to defective superoxide dismutase.

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Share to Amyotrophic Lateral Sclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18373888
DOI: 10.1186/gb-2008-9-3-214
PMCID: PMC2397497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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