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Article

Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases.

Science China. Life sciences - 1 Apr 2014

Chen Xiang-Jun, Xu Huan, Cooper Helen M, Liu Yaobo

Abstract excerpt

Cytoplasmic dynein is the most important molecular motor driving the movement of a wide range of cargoes towards the minus ends of microtubules. As a molecular motor protein, dynein performs a variety of basic cellular functions including organelle transport and centrosome assembly. In the nervous system, dynein has been demonstrated to be responsible for axonal retrograde transport. Many studies have revealed...

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Identifiers

PMID: 24664850
DOI: 10.1007/s11427-014-4639-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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