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Article

Cytoplasmic dynein heavy chain: the servant of many masters.

Trends in neurosciences - 1 Nov 2013

Schiavo Giampietro, Greensmith Linda, Hafezparast Majid, Fisher Elizabeth M C

Abstract excerpt

Cytoplasmic dynein is the main retrograde motor in all eukaryotic cells. This complex comprises different subunits assembled on a cytoplasmic dynein heavy chain 1 (DYNC1H1) dimer. Cytoplasmic dynein is particularly important for neurons because it carries essential signals and organelles from distal sites to the cell body. In the past decade, several mouse models have helped to dissect the numerous functions of...

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Identifiers

PMID: 24035135
DOI: 10.1016/j.tins.2013.08.001
PMCID: PMC3824068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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