Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Solution structure of duplex DNA containing the mutagenic lesion 1,N(2)-etheno-2'-deoxyguanine.

Biochemistry - 22 Apr 2008

Zaliznyak Tanya, Lukin Mark, Johnson Francis, de los Santos Carlos

Abstract excerpt

We have used high-resolution NMR spectroscopy and molecular dynamics simulations to determine the solution structure of DNA containing the genotoxic lesion 1, N (2)-etheno-2'-deoxyguanosine (epsilonG), paired to dC. The NMR data suggest the presence of a major, minimally perturbed structure at ne...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Guanine
Share to Hydrogen Bonding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Magnetic Resonance Spectroscopy

Share to Models, Molecular

Share to Mutation

Share to Nucleic Acid Conformation

Source

Identifiers

PMID: 18373352
DOI: 10.1021/bi7022514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18373352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Solution structure of duplex DNA containing the mutagenic lesion 1,N(2)-etheno-2'-deoxyguanine.PMID 18373352Read ↗

DNA adduct structure-function relationships: comparing solution with polymerase structures.Semantic proximity Read ↗

Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine.Semantic proximity Read ↗

High-resolution structure of a mutagenic lesion in DNA.Semantic proximity Read ↗

Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot context.Semantic proximity Read ↗

Formation of etheno adducts and their effects on DNA polymerases.Semantic proximity Read ↗

Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.Semantic proximity Read ↗

Synthesis of 3,N4-etheno, 3,N4-ethano, and 3-(2-hydroxyethyl) derivatives of 2'-deoxycytidine and their incorporation into oligomeric DNA.Semantic proximity Read ↗

Monitoring DNA-Ligand Interactions in Living Human Cells Using High-Resolution NMR SpectroscopySemantic proximity Read ↗

Investigation of the cyclobutane pyrimidine dimer (CPD) photolyase DNA recognition mechanism by NMR analyses.Semantic proximity Read ↗

O6-methylguanine and A.C and G.T mismatches cause asymmetric structural defects in DNA that are affected by DNA sequence.Semantic proximity Read ↗

Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(CTTTTGCAAAAG)(2).Semantic proximity Read ↗

[Molecular mechanisms of mutations, arising during formation of 8-hydroxyguanine in DNA].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.