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Article

[Molecular mechanisms of mutations, arising during formation of 8-hydroxyguanine in DNA].

Molekuliarnaia biologiia - 1 Jan 2000

Poltev V I, Chuprina V P, Nesterova E N

Abstract excerpt

To reveal the molecular mechanisms of genotoxic effects of oxidation and irradiation, molecular mechanics computations were performed for double-helical olygonucleotides with 8-oxoguanine:adenine (OG.A) pairs in two configurations. Substitution of a T.A pair by OG(syn).A one results in minor chan...

Topics

Base Sequence
DNA
Guanine
Molecular Sequence Data
Mutation
Nucleic Acid Conformation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7990832

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7990832-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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