Article
A new hepatitis B virus vaccine escape mutation in a renal transplant recipient.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Feb 2007
Sayiner A Arzu, Agca Harun, Sengonul Aylin, Celik Ali, Akarsu Mesut
Abstract excerpt
Surface antigen mutations of hepatitis B virus (HBV) may lead to immune escape and cause failure of immunization. In this report, the development of a chronic HBV infection in a vaccinated renal transplant recipient with pre-existing anti-HBs antibody is documented. The sequencing data showed that the HBV strain carried five amino acid substitutions in the major hydrophilic region of the S protein, one (sS143L)...
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