Article
MLLT3 regulates early human erythroid and megakaryocytic cell fate.
Cell stem cell - 6 Mar 2008
Pina Cristina, May Gillian, Soneji Shamit, Hong Dengli, Enver Tariq
Abstract excerpt
Regulatory mechanisms of human hematopoiesis remain largely uncharacterized. Through expression profiling of prospectively isolated stem and primitive progenitor cells as well as committed progenitors from cord blood (CB), we identified MLLT3 as a candidate regulator of erythroid/megakaryocytic (E/Meg) lineage decisions. Through the analysis of the hematopoietic potential of primitive cord blood cells in which...
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