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Article

Current understanding of human megakaryocytic-erythroid progenitors and their fate determinants

13 Nov 2020

Abstract excerpt

PURPOSE OF REVIEW: This review focuses on our current understanding of fate decisions in bipotent megakaryocyte-erythroid progenitors (MEPs). Although extensive research has been carried out over decades, our understanding of how MEP commit to the erythroid versus megakaryocyte fate remains unclear. RECENT FINDINGS: We discuss the isolation of primary human MEP, and focus on gene expression patterns, epigenetics,...

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PMID: 33186151
DOI: 10.1097/moh.0000000000000625

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