Article
Influence of leukotriene gene polymorphisms on chronic rhinosinusitis.
BMC medical genetics - 26 Mar 2008
Al-Shemari Hasan, Bossé Yohan, Hudson Thomas J, Cabaluna Myrna, Duval Melanie, Lemire Mathieu, Vallee-Smedja Sophie, Frenkiel Saul, Desrosiers Martin
Abstract excerpt
BACKGROUND: Chronic rhinosinusitis (CRS) is increasingly viewed as an inflammatory condition of the sinonasal mucosa interacting with bacteria and/or fungi. However, factors conferring susceptibility to disease remain unknown. Advances in genomics offer powerful tools to explore this disorder. The goal of this study was to evaluate the effect of single nucleotide polymorphisms (SNP) on CRS in a panel of genes...
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