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Article

Physiopathology and genetics in aspirin-exacerbated respiratory disease.

Experimental lung research - 1 Oct 2017

Pavón-Romero Gandhi F, Ramírez-Jiménez Fernando, Roldán-Alvarez Marco Alejandro, Terán Luis M, Falfán-Valencia Ramcés

Abstract excerpt

INTRODUCTION: Aspirin-exacerbated respiratory disease (AERD) is a clinical entity characterized by hypersensitivity to aspirin leading to asthma and chronic rhinosinusitis with nasosinusal polyposis. The pathophysiology of the disease involves disruption at the level of arachidonic acid metabolism. Therefore, genetic association studies have been focused on the genes coding this pathway. As other mechanisms...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29035123
DOI: 10.1080/01902148.2017.1358776

Genes

ALOX5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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