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Article

Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis

27 Feb 2008

Abstract excerpt

BACKGROUND: Several studies have suggested that microsatellite instability (MSI) resulting from defective DNA mismatch repair confers a better prognosis in colorectal cancer (CRC). Recently, however, data have suggested this is secondary to the effects of ploidy/chromosomal instability (CIN). To estimate the prognostic significance of CIN for survival, data from published studies have been reviewed and pooled....

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Share to Colorectal Cancer Screening and Detection
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18364437
DOI: 10.1136/gut.2007.135004

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