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Article

Relationship between genetic alterations and prognosis in sporadic colorectal cancer

17 Oct 2005

Abstract excerpt

Because chromosomal chromosomal instability (CIN) and microsatellite instability (MSI) are important genetic alterations in colorectal cancers, we classified the sporadic colorectal cancers (CRC) on the status of the CIN and MSI and explored their molecular profiles. A total of 213 colorectal tumors were collected for analysis of DNA ploidy, MSI, loss of heterozygosity (LOH), mutation of p53 (exons 5 to 9),...

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PMID: 16231316
DOI: 10.1002/ijc.21563

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