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Article

Microsatellite Instability and Colorectal Cancer Prognosis

1 Dec 2005

Abstract excerpt

PURPOSE: Many studies have evaluated the role of high levels of microsatellite instability (MSI) as a prognostic marker and predictor of the response to chemotherapy in colorectal cancer (CRC); however, the results are not conclusive. The aim of this study was to analyze the prognostic significance of high levels of MSI (MSI-H) in CRC patients in relation to fluorouracil-based chemotherapy. EXPERIMENTAL DESIGN:...

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PMID: 16322293
DOI: 10.1158/1078-0432.ccr-05-1030

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