Article
Genetic alterations in locally advanced stage II/III colon cancer: a search for prognostic markers.
Clinical colorectal cancer - 1 Nov 2004
Westra Jantine L, Plukker John T, Buys Charles H, Hofstra Robert M
Abstract excerpt
Heterogeneity in advanced colon cancer leads to different results from adjuvant chemotherapy. To identify groups of patients who may need adjuvant treatment, molecular staging and correlation with clinical data may be helpful in classifying histologically similar tumors. Colon cancer develops through a multistep process with an accumulation of multiple genetic alterations that are often the cause of a form of...
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