Article
Genetic variations and gene expression of transporters in drug disposition and response.
Expert opinion on drug metabolism & toxicology - 1 Mar 2008
Huang Ying, Penchala Sravan, Pham Anh-Nhan, Wang Jeffrey
Abstract excerpt
BACKGROUND: The importance of transporters in drug disposition and response has led to increasing interest in genetic variations and expression differences of their genes. OBJECTIVE: This review summarizes: i) genetic variations in transporters and associated drug response; and ii) a pharmacogenomic approach to correlate transporter expression and drug response. METHODS: Several transporters in ATP-binding...
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