Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of genetic variation in OATP transporters to drug disposition and response.

Drug metabolism and pharmacokinetics - 1 Jan 2013

Gong Inna Y, Kim Richard B

Abstract excerpt

There has been remarkable progress during the past decade in understanding of how genetic variations in drug metabolizing enzymes and transporters contribute to observed variation in drug responsiveness. Among drug transporters, the organic anion transporting polypeptide (OATP) class of transporters have proven to be remarkably important to the cellular uptake disposition of a variety of clinically important...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genotype
Share to Liver-Specific Organic Anion Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organic Anion Transporters

Share to Pharmaceutical Preparations

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 23047721
DOI: 10.2133/dmpk.dmpk-12-rv-099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of genetic variation in OATP transporters to drug disposition and response.PMID 23047721Read ↗

Genetic Polymorphisms of OATP Transporters and Their Impact on Intestinal Absorption and Hepatic Disposition of DrugsSemantic proximity Read ↗

Pharmacogenomics of the OATP and OAT families.Semantic proximity Read ↗

The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literatureSemantic proximity Read ↗

Genetic polymorphisms of human hepatic OATPs: functional consequences and effect on drug pharmacokineticsSemantic proximity Read ↗

Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation.Semantic proximity Read ↗

Pharmacogenetics of the organic anion transporting polypeptide 1A2.Semantic proximity Read ↗

Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions.Semantic proximity Read ↗

The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.Semantic proximity Read ↗

Pharmacogenetics of membrane transporters: a review of current approaches.Semantic proximity Read ↗

Impact of drug transporter pharmacogenomics on pharmacokinetic and pharmacodynamic variability - considerations for drug development.Semantic proximity Read ↗

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.Semantic proximity Read ↗

Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.