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Article

Association of PTPRB gene polymorphism with drug addiction.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008

Ishiguro Hiroki, Gong Jian-Ping, Hall F Scott, Arinami Tadao, Uhl George R

Abstract excerpt

Several lines of evidence support the involvement of protein tyrosine phosphatase receptor type beta (PTPRB) in addiction. Generally, PTPs interact with both neuronal receptors and cell adhesion molecules, and appear to play roles in neurite growth and neuronal differentiation. We previously identified a role of the cell adhesion molecule NrCAM in polysubstance abuse vulnerability in humans, as well as in the...

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Source

Identifiers

PMID: 18361428
DOI: 10.1002/ajmg.b.30742

Genes

PTPRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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